Isotopically Labeled Compounds
Medchemexpress LLC Salicylic acid-d6 (2-hydroxybenzoic acid-d6) | 285979-87-5 | 99.8% | 1 MG
Salicylic acid-d6 is a deuterium labeled Salicylic acid that inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. It is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Metronidazole-d3 | 83413-09-6 | MFCD27702816 | 100.0% | 1 MG
Metronidazole-d3 is a deuterium-labeled form of Metronidazole. It can be used for research purposes, including as a tracer or an internal standard for quantitative analysis by techniques like NMR, GC-MS, or LC-MS. This compound typically appears as a light yellow to yellow solid.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Contains stable heavy isotopes incorporated into drug molecules.
- Deuteration offers potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sulfamethoxazole-d4 | 1020719-86-1 | 99.3% | 1 ML
Sulfamethoxazole-d4 is a deuterium-labeled sulfonamide antibiotic, also known as Ro 4-2130-d4. It demonstrates widespread antibacterial activity by inhibiting bacterial folate metabolism, specifically by competing with 4-Aminobenzoic acid (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. This product is intended for research use only.
- Deuterium labeled analog
- Sulfonamide antibiotic with widespread antibacterial activity
- Inhibits bacterial folate metabolism
- Suitable for studying urinary tract infections (UTIs), prostatitis, and bronchitis
- Supplied as a 10 mM solution in DMSO
Medchemexpress LLC Estrone-d4 | 53866-34-5 | 99.5% | 1 MG
Estrone-d4 is the deuterium-labeled version of Estrone (E1), a natural estrogenic hormone. Estrone is a primary endogenous estrogen, produced predominantly by adipose tissue. It is formed through the aromatization of androstenedione in fat cells. Deuterium substitution in drug molecules is used as a tracer for quantitation in drug development and has the potential to influence pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Riboflavin-d3 | 83-88-5 | 99.9% | 1 MG
Riboflavin-d3 is a deuterium-labeled form of Riboflavin (Vitamin B2). Riboflavin is an easily absorbed micronutrient essential for maintaining health in humans and other animals. This compound is intended for research use only and can be utilized as a tracer or an internal standard for quantitative analysis. Deuterium substitution has been noted for its potential impact on the pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories TETRAHYDROFURAN-D8"100%-10X.75
Tetrahydrofuran-d8 100% (d, 99.95%)-10x0.75 Ml
Medchemexpress LLC Nad+-13c5 ammonium | 53-84-9 | 98.9% | 1 MG
NAD+-13C5 (ammonium) is a 13C labeled NAD+ compound intended for research use only. This compound can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Stable heavy isotopes are incorporated into drug molecules primarily as tracers for quantitation during drug development. Shipping is at room temperature in the continental US, with variations elsewhere. Solid storage requires -20°C, sealed, away from moisture and light. If in solvent, store at -80°C for 6 months or -20°C for 1 month, also sealed and away from moisture and light.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Trospium-d8 chloride | 10405-02-4 | 1 MG
Trospium-d8 (chloride) is the deuterium-labeled form of Trospium chloride. Trospium chloride is an orally active, specific, and competitive antagonist of muscarinic cholinergic receptors (mAChRs), exhibiting antimuscarinic activity. It binds with high affinity to muscarinic receptors M1, M2, and M3, but not nicotinic cholinergic receptors.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporation of stable heavy isotopes can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Ronidazole-d3 | 1015855-87-4 | MFCD09265285 | 5 MG
Ronidazole-d3 is the deuterium-labeled version of Ronidazole. It is an effective orally active antiprotozoal and anti-microbial agent used as a veterinary agent against Tritrichomonas foetus in cat models and in research for histomoniasis and swine dysentery.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes can be incorporated into drug molecules as tracers for quantitation during drug development.
- Deuteration has potential to influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Hercynine-d3 | 1639966-63-4 | 99.8% | C9H12D3N3O2 | 2.5 MG
L-Hercynine-d3 is the deuterium labeled L-Hercynine. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Deuterium labeling can impact pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC C18 glucosyl(β) ceramide (d18:1/18:0) | 95119-86-1 | 99.9% | 728.09 g/mol | C42H81NO8 | 10 MG
GlcCer (d18:1/18:0) is a C18 glucosylceramide glycosphingolipid used as a biochemical research reagent for studies of glycosphingolipid metabolism and neurodegenerative disorders, including Parkinson disease and dementia with Lewy bodies. The compound is supplied as a solid for dissolution in organic solvent and is characterized by formula C42H81NO8 and molecular weight 728.09 g/mol.
- Used in studies of glycosphingolipid biology and neurodegeneration.
- Suitable for biochemical and cellular assays.
- Soluble in DMSO; ultrasonic treatment may be required for full dissolution.
- Stable as powder at -20°C for extended storage.
- High purity appropriate for research applications.
Cayman Chemical DIclofenac-d4 500ug
An internal standard for the quantification of diclofenac by GC- or LC-MS
Medchemexpress LLC 5'-guanylic acid-15N5 dilithium | 85-32-5 | MFCD00057066 | 95.0% | 380.05 g/mol | C10H12Li215N5O8P | 10 MG
5'-Guanylic acid-15N5 dilithium is the 15N5 isotopically labeled dilithium salt of guanosine 5'-monophosphate supplied as a small analytical package. It is intended for use as an isotopic tracer and internal standard in quantitative analytical methods, including NMR, GC-MS, and LC-MS.
- 15N5-labeled dilithium salt form for isotopic tracing
- Intended as tracer and internal standard for quantitative NMR, GC-MS, and LC-MS
- Purity 95.0% suitable for analytical applications
- Molecular weight 380.05 g/mol
- Provided as a 10 mg solid package for laboratory use